Lesson 967 of 1524
Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions
Acid halides, acid anhydrides, esters, and amides are the most common such derivatives in the laboratory; thioesters and acyl phosphates are common in biological molecules
Practice this chapterAcid halides, acid anhydrides, esters, and amides are the most common such derivatives in the laboratory; thioesters and acyl phosphates are common in biological molecules The chemistry of carboxylic acid derivatives is dominated by the nucleophilic acyl substitution reaction .
The reactivity order is acid halide > acid anhydride > thioester > ester > amide Carboxylic acid derivatives —compounds in which the -OH group of a carboxylic acid has been replaced by another substituent—are among the most widely occurring of all molecules and are involved in almost all biological…
chemistry of carboxylic acid derivatives — dominated by the nucleophilic acyl substitution reaction. reactivity order — acid halide > acid anhydride > thioester > ester > amide. laboratory; thioesters and acyl phosphates — common in biological molecules.
Worked example
What does “chemistry of carboxylic acid derivatives” mean in Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions?
- 1Use the wording this chapter gives for chemistry of carboxylic acid derivatives.
- 2The book says: dominated by the nucleophilic acyl substitution reaction.
- 3Do not use the meaning of reactivity order. That term means acid halide > acid anhydride > thioester > ester > amide.
Result: dominated by the nucleophilic acyl substitution reaction
Why. That is the meaning this chapter gives for chemistry of carboxylic acid derivatives.
Do not swap chemistry of carboxylic acid derivatives and reactivity order. chemistry of carboxylic acid derivatives means dominated by the nucleophilic acyl substitution reaction. reactivity order means acid halide > acid anhydride > thioester > ester > amide.
Practice margin
This chapter
A fresh set from this chapter only. Choose 10 or 20. Multiple choice and fill-in, with no repeat inside the set.